It resulted in the creation of multiple production and research sites that operated in secret. With the total involved, this makes it one of the largest conspiracies in history. Entire towns were built for short periods of time, employing people, all under secrecy and top national secrecy at that. The government never admitted to it, the media never reported on it, and people had no idea for over 25 years.
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Tamoxifenstimulated growth seems to result from the gene PAX2 (paired box gene 2) becoming hypomethylated in endometrial cancer, and both oestrogen and tamoxifen can increase the proliferation and growth of endometrial tumours through an oestrogen receptor and PAX2mediated mechanism92. Nevertheless, based on the fact that tamoxifen is a complete carcinogen in the rat liver, owing to the formation of DNA adducts by hydroxytamoxifen (see figure), considerable effort has focused on identifying DNA adducts in humans93, 94. No unifying molecular mechanism of causation is universally accepted. However, recent reports about the direct carcinogenic activity of oestrogen for the causation of breast cancer95, 96 might have some relevance to events in the uterus..
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The Clippers (4823), who couldn't build upon leads of 7061 in the third quarter and 8780 midway through the fourth, are locked in a threeway battle with Denver and Memphis for the third seed in the Western Conference. The loss, which snapped a twogame win streak, dropped them to fourth place behind Denver. Tuesday was the first of four road games in five nights that includes stops at New Orleans on Wednesday followed by San Antonio and Houston.
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