Based on a multiple dose cross study comparison, the apparent volume of distribution for acrivastine was 44% lower in elderly (n = 36, 65-75 yr) than in young volunteers (n = 16, 19-33 yr).
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Investigation for low platelet count includes a comprehensive medical history and physical examination by the doctor.
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The prognosis (chance of recovery) depends on the size and stage of the tumor, response to treatment, symptoms, characteristics of the tumor cells, and whether the cancer was newly diagnosed or recurred.
A meal slows absorption of losartan and decreases its Cmax but has only minor effects on losartan AUC or on the AUC of the metabolite (about 10% decreased).