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In an 18-month study using doses of about 50, 150 and 500 mg/kg/day, there were statistically significant increases in benign adenomas of the thyroid and testes and, in male rats, a dose-related increase in proliferative changes in the liver (including hepatocytomegaly and hyperplastic nodules).
Insulin promotes a transcellular shift of potassium into cells.
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The service is available from 9:00 a.m. to 11:00 p.m. Eastern time, Monday through Friday.
Editors:&nbsp;N Stuart Harris, MD, MFA, Staff Physician, Department of Emergency Medicine, Harvard Medical School; Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine; James Kimo Takayesu, MD, Staff Physician, Department of Emergency Medicine, Brigham and Women's Hospital/Massachusetts General Hospital.