Drug-induced secondary adrenocortical insufficiency may result from too rapid withdrawal of corticosteroids and may be minimized by gradual reduction of dosage.
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Reported effects include hypotension, bradycardia, cardiac conduction defects, arrhythmias, hyperglycemia, and decreased mental status.
Sumycin Syrup (Tetracycline Oral Suspension, USP) is a suspension containing, in each 5 mL teaspoonful, tetracycline equivalent to 125 mg tetracycline hydrochloride.
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It is uncertain whether this case represented a drug-drug interaction, a response to either drug alone, or some other cause.
For prolonged therapy, the total daily dose may be reduced to 15 mg/lb/day (33 mg/kg/day).