tions, but reflects the reality of clinical research. 聽 As you can imagine, the more restrictive the enrollment criteria are, the be er the investigators will be at teasing out the specifics of their hypothesis, though the less generalizable the conclusions may be. As you and many of your readers may know, we are currently engaged in a much larger registry study out in the community, discount hockey jerseys where gt patients will be studied with many fewer restrictions in enrollment. 聽 We hope that this study will answer the questions that we and others have about referral bias. In our published studies, we enrolled a consecutive series of patients referred to my tertiary autonomic function clinic with a diagnosis of POTS. 聽 In practice, we excluded very few patients with underlying disorders, in part because as you suggested in your review, most of these patients had seen many other doctors before being referred to me, similar to the patient populations at the Mayo Clinic or Vanderbilt. From discussing our patient population with those of other experts and we often see each others' patients. in the field, I wholesale nfl jerseys am confident that our population is representative of the broad referral population of POTS patients. Regarding "Grinch Syndrome. " Finally, let me finish with a few cheap soccer jerseys words about the Grinch. 聽 The vast majority of our patients who hear the term "The Grinch Syndrome" laugh and take comfort in the spirit in which it is presented. On the other hand, I understand that some patients who don't know me, and are concerned with being labeled by a name that is associated with being mean spirited, object to the use of the term Grinch Syndrome, and I respect those concerns. 聽 Frankly, if I had to do it over again, I probably would have been more reluctant to use the

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